Napoli striker Gonzalo Higuain has been left out of Argentina's latest squad with Juventus youngster Paulo Dybala preferred instead.
Higuain, 27, has scored four goals in five Serie A games for Napoli this season, but Argentina boss Gerardo "Tata" Martino has opted not use the former Real Madrid forward in two opening World Cup qualifying games against Ecuador and Paraguay.
Dybala, the 21-year-old who left Palermo to join Juve in the summer, receives a first call-up after notching two goals in his three league appearances for the Bianconeri.
Another new face in Martino's Albiceleste selection is River Plate defensive midfielder Matias Kranevitter, while forward Angel Correa of Atletico Madrid is included once again having made his senior international debut against Bolivia earlier this month in a friendly.
Argentina host Ecuador in Buenos Aires on Oct. 8 before facing Paraguay in Asuncion five days later.
Complete squad:
Goalkeepers: Sergio Romero, Nahuel Guzman, Agustin Marchesin.
Defenders: Emmanuel Mas, Facundo Roncaglia, Ezequiel Garay, Nicolas Otamendi, Marcos Rojo, Milton Casco, Ramiro Funes Mori, Martín Demichelis, Pablo Zabaleta.
Midfielders: Ever Banega, Matias Kranevitter, Javier Mascherano, Lucas Biglia, Roberto Pereyra, Javier Pastore, Enzo Pérez, Nicolas Gaitan, Angel Di María.
Forwards: Carlos Tevez, Paulo Dybala, Ezequiel Lavezzi, Angel Correa, Lionel Messi, Sergio Aguero.